Anti-Human ERLIN2 Polyclonal Antibody (HF861014)

Name: Anti-Human ERLIN2 Polyclonal Antibody
Brand: abinScience
SKU: HF861014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HF861014

설명

Anti-Human ERLIN2 Polyclonal Antibody (HF861014) is a rabbit polyclonal antibody detecting ERLIN2. Suitable for Rat, Mouse, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ERLIN2 (Pro47-Asn339).

타겟

C8orf2, ERLIN2, Endoplasmic reticulum lipid raft-associated protein 2, Erlin-2, SPFH domain-containing protein 2, SPFH2, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O94905

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Erlin-2 (ERLIN2) is a ~37 kDa protein. Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.

1. Pearce, MM. et al. (2007) The Journal of biological chemistry 282, 20104-15. PMID: 17502376

2. Pearce, MM. et al. (2009) The Journal of biological chemistry 284, 10433-45. PMID: 19240031

3. Jo, Y. et al. (2011) The Journal of biological chemistry 286, 15022-31. PMID: 21343306

4. Huber, MD. et al. (2013) The Journal of cell biology 203, 427-36. PMID: 24217618

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human ERLIN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ERLIN2 Polyclonal Antibody (HF861014)

개요

이미지

참고 문헌

데이터시트

SDS