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Anti-Human FABP5 Polyclonal Antibody (HX954014)

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개요
카탈로그 번호HX954014
설명
Anti-Human FABP5 Polyclonal Antibody (HX954014) is a rabbit polyclonal antibody detecting FABP5 in ELISA, IHC, WB. Suitable for Human and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human FABP5 (Met1-Glu135).
타겟 Psoriasis-associated fatty acid-binding protein homolog, FABP5, E-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein, epidermal, Fatty acid-binding protein 5, PA-FABP
정제 Purified by antigen affinity column.
등록번호 Q01469
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Fatty acid-binding protein 5 (FABP5) is a ~15 kDa protein. Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation.

1. Mitchell, RW. et al. (2011) Journal of neurochemistry 117, 735-46. PMID: 21395585
2. Kaczocha, M. et al. (2012) The Journal of biological chemistry 287, 3415-24. PMID: 22170058
3. Siegenthaler, G. et al. (1994) The Biochemical journal 302 ( Pt 2), 363-71. PMID: 8092987
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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