中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HT042013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1792 | ||||
| 타겟 | D5D, FADS1, Delta(5) fatty acid desaturase, Acyl-CoA (8-3)-desaturase, Fatty acid desaturase 1, Delta(5) desaturase, Delta-5 desaturase, FADSD5 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | O60427 | ||||
| RRID | Anti-Human FADS1/Delta 5 desaturase Antibody (SAA1792) (abinScience Cat# HT042013, RRID:AB_3727554) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Acyl-CoA (8-3)-desaturase (FADS1/Delta 5 desaturase) is a ~51 kDa protein. Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end of the fatty acyl chain. Involved in biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors. Specifically, desaturates dihomo-gamma-linoleoate (DGLA) (20:3n-6) and eicosatetraenoate (ETA) (20:4n-3) to generate arachidonate (AA) (20:4n-6) and eicosapentaenoate (EPA) (20:5n-3), respectively. As a rate limiting enzyme for DGLA (20:3n-6) and AA (20:4n-6)-derived eicosanoid biosynthesis, controls the metabolism of inflammatory lipids like prostaglandin E2, critical for efficient acute inflammatory response and maintenance of epithelium homeostasis. Contributes to membrane phospholipid biosynthesis by providing AA (20:4n-6) as a major acyl chain esterified into phospholipids. 1. Cho, HP. et al. (1999) The Journal of biological chemistry 274, 37335-9. PMID: 10601301 2. Leonard, AE. et al. (2000) The Biochemical journal 347 Pt 3, 719-24. PMID: 10769175 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human FADS1/Delta 5 desaturase Antibody (SAA1792)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
