Anti-Human FCN2 Polyclonal Antibody (HS794014)

Name: Anti-Human FCN2 Polyclonal Antibody
Brand: abinScience
SKU: HS794014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HS794014

설명

Anti-Human FCN2 Polyclonal Antibody (HS794014) is a rabbit polyclonal antibody detecting FCN2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human FCN2 (Thr47-Asn300).

타겟

Hucolin, FCNL, Collagen/fibrinogen domain-containing protein 2, 37 kDa elastin-binding protein, Serum lectin p35, Ficolin-2, EBP-37, FCN2, Ficolin-beta, L-ficolin, Ficolin-B

정제

Purified by antigen affinity column.

등록번호

Q15485

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ficolin-2 (FCN2) is a ~34 kDa protein. Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway. Specifically binds N-Acetylglucosamine (GlcNAc), as well as phosphocholine and lipoteichoic acid moieties on the surface of pathogens. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect.

1. Matsushita, M. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 2281-4. PMID: 10679061

2. Lynch, NJ. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 1198-202. PMID: 14707097

3. Kuraya, M. et al. (2005) Immunobiology 209, 689-97. PMID: 15804047

4. Garlatti, V. et al. (2007) The EMBO journal 26, 623-33. PMID: 17215869

5. Vassal-Stermann, E. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 5699-708. PMID: 25344472

6. Matsushita, M. et al. (1996) The Journal of biological chemistry 271, 2448-54. PMID: 8576206

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human FCN2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human FCN2 Polyclonal Antibody (HS794014)

개요

이미지

참고 문헌

데이터시트

SDS