

| 카탈로그 번호 | HC469014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human FLII Polyclonal Antibody (HC469014) is a rabbit polyclonal antibody detecting FLII in ELISA, IHC, WB. Suitable for Mus musculus and Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human FLII (Leu896-Phe1176). | ||||||||
| 타겟 | FLII | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q13045 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | Protein flightless-1 homolog, FLII, FLIL | ||||||||
| 배경 | Protein flightless-1 homolog (FLII) is a ~144 kDa protein. Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. 1. Lee, YH. et al. (2004) Molecular and cellular biology 24, 2103-17. PMID: 14966289 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-FLII polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: A549 cell lysate


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