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| 카탈로그 번호 | HB265195 |
|---|---|
| 설명 |
Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A418) [1A418] (HB265195) is a mouse monoclonal antibody detecting VEGFR1 in ELISA. Suitable for Human.
|
| 종 반응성 | Human |
| 응용 분야 | ELISA |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | 1A418 |
| 면역원 | Human FLT1/VEGFR1 Protein. |
| 타겟 | Vascular endothelial growth factor receptor 1, VEGFR-1, 2.7.10.1, Fms-like tyrosine kinase 1, FLT-1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, FLT, Vascular permeability factor receptor, FLT1, FLT, FRT, VEGFR1 |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P17948 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Vascular endothelial growth factor receptor 1 (FLT1/VEGFR1) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. 1. Lesslie, DP. et al. (2006) British journal of cancer 94, 1710-7. PMID: 16685275 |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human FLT1/VEGFR1 Monoclonal Antibody (1A418)
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