

| 카탈로그 번호 | HD654014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human FMN2 Polyclonal Antibody (HD654014) is a rabbit polyclonal antibody detecting FMN2. Suitable for Mouse and Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human FMN2 (Ser1361-Thr1722). | ||||||||
| 타겟 | FMN2, Formin-2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9NZ56 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Formin-2 (FMN2) is a ~180 kDa protein. Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. 1. Vizcarra, CL. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 11884-9. PMID: 21730168 2. Peng, KW. et al. (2012) Biochimica et biophysica acta 1820, 469-81. PMID: 22330775 3. Yamada, K. et al. (2013) Molecular cell 49, 922-33. PMID: 23375502 4. Belin, BJ. et al. (2015) eLife 4, e07735. PMID: 26287480 | ||||||||
| 참고사항 | For research use only |
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