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| 카탈로그 번호 | HB825023 |
|---|---|
| 설명 |
Anti-Human FOLR1 Nanobody (SAA2797) (HB825023) is a alpaca monoclonal antibody detecting Human FOLR1. Suitable for Human.
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Alpaca |
| 클론성 | Monoclonal |
| 이소타입 | VHH-8His-Cys-tag |
| 클론 ID | SAA2797 |
| 타겟 | ANPEP, AP-M, AP-N, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, CD13, EC:3.4.11.2, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150, hAPN |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P15144 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Aminopeptidase N (FOLR1) is a ~109 kDa protein. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. FOLR1 is the therapeutic target of mirvetuximab soravtansine (Elahere). |
| 참고사항 | For research use only |
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