Anti-Human FOSB Polyclonal Antibody (HD091014)

Name: Anti-Human FOSB Polyclonal Antibody
Brand: abinScience
SKU: HD091014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD091014

설명

Anti-Human FOSB Polyclonal Antibody (HD091014) is a rabbit polyclonal antibody detecting Protein FosB. Suitable for Rat, Mouse, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human FOSB (Phe2-Leu338).

타겟

FOSB, FosB proto-oncogene, AP-1 transcription factor subunit, G0/G1 switch regulatory protein 3, G0S3, Protein FosB, Transcription factor AP-1 subunit FosB

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P53539

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Protein FosB is a ~35 kDa protein. Heterodimerizes with proteins of the JUN family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to gene promoters containing an AP-1 consensus sequence 5'-TGA[GC]TCA-3' and enhancing their transcriptional activity. As part of the AP-1 complex, facilitates enhancer selection together with cell-type-specific transcription factors by collaboratively binding to nucleosomal enhancers and recruiting the SWI/SNF (BAF) chromatin remodeling complex to establish accessible chromatin. Together with JUN, plays a role in activation-induced cell death of T cells by binding to the AP-1 promoter site of FASLG/CD95L, and inducing its transcription in response to activation of the TCR/CD3 signaling pathway. Exhibits transactivation activity in vitro. Involved in the display of nurturing behavior towards newborns.

1. Baumann, S. et al. (2003) Oncogene 22, 1333-9. PMID: 12618758

2. Yin, Z. et al. (2017) Nucleic acids research 45, 11425-11436. PMID: 28981703

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human FOSB Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human FOSB Polyclonal Antibody (HD091014)

개요

이미지

참고 문헌

데이터시트

SDS