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Anti-Human FOXP1 Polyclonal Antibody (HV703014)

Anti-Human FOXP1 Polyclonal Antibody
Anti-Human FOXP1 Polyclonal Antibody
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  • 개요

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개요
카탈로그 번호HV703014
설명
Anti-Human FOXP1 Polyclonal Antibody (HV703014) is a rabbit polyclonal antibody detecting FOXP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human FOXP1 (Asn461-Pro671).
타겟 FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead
정제 Purified by antigen affinity column.
등록번호 Q9H334
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Forkhead box protein P1 (FOXP1) is a ~75 kDa protein. Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development.

1. Jepsen, K. et al. (2008) Genes & development 22, 740-5. PMID: 18347093
2. Sollis, E. et al. (2016) Human molecular genetics 25, 546-57. PMID: 26647308
3. van Keimpema, M. et al. (2014) Blood 124, 3431-40. PMID: 25267198
4. Shi, C. et al. (2004) The Journal of clinical investigation 114, 408-18. PMID: 15286807
5. Shi, C. et al. (2008) Blood 112, 4699-711. PMID: 18799727
6. Grundmann, S. et al. (2013) PloS one 8, e70873. PMID: 24023716
7. Takayama, K. et al. (2008) Biochemical and biophysical research communications 374, 388-93. PMID: 18640093
8. Kamran, M. et al. (2017) Oncogenesis 6, e298. PMID: 28218735
참고사항 For research use only.
이미지
  • Anti-Human FOXP1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-FOXP1 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Jurkat cell lysate
    Lane 2: MCF-7 cell lysate

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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