

| 카탈로그 번호 | HV703014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human FOXP1 Polyclonal Antibody (HV703014) is a rabbit polyclonal antibody detecting FOXP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human FOXP1 (Asn461-Pro671). | ||||||||
| 타겟 | FOXP1, MFH, Forkhead box protein P1, Mac-1-regulated forkhead | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9H334 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Forkhead box protein P1 (FOXP1) is a ~75 kDa protein. Transcriptional repressor. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. 1. Jepsen, K. et al. (2008) Genes & development 22, 740-5. PMID: 18347093 2. Sollis, E. et al. (2016) Human molecular genetics 25, 546-57. PMID: 26647308 3. van Keimpema, M. et al. (2014) Blood 124, 3431-40. PMID: 25267198 4. Shi, C. et al. (2004) The Journal of clinical investigation 114, 408-18. PMID: 15286807 5. Shi, C. et al. (2008) Blood 112, 4699-711. PMID: 18799727 6. Grundmann, S. et al. (2013) PloS one 8, e70873. PMID: 24023716 7. Takayama, K. et al. (2008) Biochemical and biophysical research communications 374, 388-93. PMID: 18640093 8. Kamran, M. et al. (2017) Oncogenesis 6, e298. PMID: 28218735 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-FOXP1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: MCF-7 cell lysate


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