

| 카탈로그 번호 | HB940014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human FUT1 Polyclonal Antibody (HB940014) is a rabbit polyclonal antibody detecting FUT1. Suitable for Human.
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human FUT1 (Thr80-Pro365). | ||||||||
| 타겟 | Alpha(1,2)FT 1, Blood group H alpha 2-fucosyltransferase, EC:2.4.1.344, EC:2.4.1.69, FUT1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Galactoside alpha-(1,2)-fucosyltransferase 1, H, HSC, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P19526 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Galactoside alpha-(1,2)-fucosyltransferase 1 (FUT1) is a ~41 kDa protein. Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a. 1. Larsen, RD. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 6674-8. PMID: 2118655 2. Moehler, TM. et al. (2008) Journal of cellular physiology 215, 27-36. PMID: 18205178 | ||||||||
| 참고사항 | For research use only |
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