Anti-Human Glucagon R/GCGR Recombinant Antibody (SAA0132), APC (HW547137)

Name: Anti-Human Glucagon R/GCGR Recombinant Antibody (SAA0132), APC
Brand: abinScience
SKU: HW547137
Price: 290 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
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개요

카탈로그 번호	HW547137
종 반응성	Human
응용 분야	FCM
숙주 종	Human
클론성	Monoclonal
이소타입	IgG2, kappa
클론 ID	SAA0132
접합	APC
타겟	GCGR, Glucagon receptor, GL-R
내독소 수준	Please contact with the lab for this information.
관련 제품	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호	P47871
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Glucagon receptor (GCGR) is a ~54 kDa protein. G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. 1. Qiao, A. et al. (2020) Science (New York, N.Y.) 367, 1346-1352. PMID: 32193322 2. Cong, Z. et al. (2024) Cell discovery 10, 18. PMID: 38346960
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.