

| 카탈로그 번호 | HT422014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human GFRA2 Polyclonal Antibody (HT422014) is a rabbit polyclonal antibody detecting GFRA2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Pongo abelii.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GFRA2 (Asp226-Ser444). | ||||||||
| 타겟 | TGF-beta-related neurotrophic factor receptor 2, RETL2, GDNFR-alpha-2, GFRA2, GFR-alpha-2, Neurturin receptor alpha, TRNR2, GDNF receptor beta, GDNF family receptor alpha-2, NRTNR-alpha, RET ligand 2, NTNR-alpha, GDNFRB, GDNF receptor alpha-2, GDNFR-beta | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O00451 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | GDNF family receptor alpha-2 (GFRA2) is a ~51 kDa protein. Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons. NRTN-binding leads to autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. 1. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012 2. Sandmark, J. et al. (2018) The Journal of biological chemistry 293, 5492-5508. PMID: 29414779 3. Li, J. et al. (2019) eLife 8. PMID: 31535977 4. Baloh, RH. et al. (1997) Neuron 18, 793-802. PMID: 9182803 | ||||||||
| 참고사항 | For research use only. |
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