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| 카탈로그 번호 | HB148013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1838 | ||||
| 타겟 | Connexin-26, Cx26, GJB2, Gap junction beta-2 protein | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P29033 | ||||
| RRID | Anti-Human GJB2 Antibody (SAA1838) (abinScience Cat# HB148013, RRID:AB_3727601) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Gap junction beta-2 protein (GJB2) is a ~26 kDa protein. Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. 1. Bicego, M. et al. (2006) Human molecular genetics 15, 2569-87. PMID: 16849369 2. Oshima, A. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 10034-9. PMID: 17551008 3. Maeda, S. et al. (2009) Nature 458, 597-602. PMID: 19340074 4. Choi, SY. et al. (2009) Human mutation 30, E716-27. PMID: 19384972 5. Oshima, A. et al. (2011) Journal of molecular biology 405, 724-35. PMID: 21094651 6. Bennett, BC. et al. (2016) Nature communications 7, 8770. PMID: 26753910 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human GJB2 Antibody (SAA1838)
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