Anti-Human GLRA1 Polyclonal Antibody (HB788014)

Name: Anti-Human GLRA1 Polyclonal Antibody
Brand: abinScience
SKU: HB788014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HB788014

설명

Anti-Human GLRA1 Polyclonal Antibody (HB788014) is a rabbit polyclonal antibody detecting GLRA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human GLRA1 (Ala32-Gln247).

타겟

Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit, Glycine receptor subunit alpha-1, GLRA1

정제

Purified by antigen affinity column.

등록번호

P23415

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Glycine receptor subunit alpha-1 (GLRA1) is a ~52 kDa protein. Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol. Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol.

1. Mohammadi, B. et al. (2003) European biophysics journal : EBJ 32, 529-36. PMID: 14551753

2. Mowrey, DD. et al. (2013) Structure (London, England : 1993) 21, 1897-904. PMID: 23994010

3. Moraga-Cid, G. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 2865-70. PMID: 25730860

4. Liu, X. et al. (2023) Nature communications 14, 6377. PMID: 37821459

5. Shiang, R. et al. (1993) Nature genetics 5, 351-8. PMID: 8298642

6. Lynch, JW. et al. (1997) The EMBO journal 16, 110-20. PMID: 9009272

7. Zhang, Y. et al. (2015) Neuropharmacology 89, 391-7. PMID: 25445488

8. Horani, S. et al. (2015) Alcoholism, clinical and experimental research 39, 962-8. PMID: 25973519

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human GLRA1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human GLRA1 Polyclonal Antibody (HB788014)

개요

이미지

참고 문헌

데이터시트

SDS