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| 카탈로그 번호 | HY277014 | ||||||||
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| 설명 |
Anti-Human GNAT1 Polyclonal Antibody (HY277014) is a rabbit polyclonal antibody detecting GNAT1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human GNAT1 (Met1-Phe350). | ||||||||
| 타겟 | Transducin alpha-1 chain, GNATR, Guanine nucleotide-binding protein G(t) subunit alpha-1, GNAT1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P11488 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Guanine nucleotide-binding protein G(t) subunit alpha-1 (GNAT1) is a ~40 kDa protein. Functions as a signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina. Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. 1. Naeem, MA. et al. (2012) Investigative ophthalmology & visual science 53, 1353-61. PMID: 22190596 | ||||||||
| 참고사항 | For research use only. |
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