Anti-Human GREM1 Recombinant Antibody (Ab7326) (HT246013)

Name: Anti-Human GREM1 Recombinant Antibody (Ab7326)
Brand: abinScience
SKU: HT246013
Price: 191 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HT246013

설명

Anti-Human GREM1 Recombinant Antibody (Ab7326) (HT246013) is a mouse monoclonal antibody detecting GREM1 in ELISA, Functional assay. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, Functional assay

숙주 종

Mouse

클론성

Monoclonal

이소타입

IgG1

클론 ID

Ab7326

타겟

CKTSF1B1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, BMP antagonist 1, DAN domain family member 2, DAND2, DRM, Down-regulated in Mos-transformed cells protein, GREM1, Gremlin-1, IHG-2, Increased in high glucose protein 2

내독소 수준

< 10 EU/mg as determined by LAL method.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

O60565

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Gremlin-1 (GREM1) is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed.

1. Kišonaitė, M. et al. (2016) The Biochemical journal 473, 1593-604. PMID: 27036124

참고사항

For research use only.

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

이미지

SDS-PAGE

SDS-PAGE for Anti-Human GREM1 Antibody (Ab7326)

참고 문헌

데이터시트

Anti-Human GREM1 Recombinant Antibody (Ab7326).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human GREM1 Recombinant Antibody (Ab7326) (HT246013)

개요

이미지

참고 문헌

데이터시트

SDS