Anti-Human HCN2 Polyclonal Antibody (HP198014)

Name: Anti-Human HCN2 Polyclonal Antibody
Brand: abinScience
SKU: HP198014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HP198014

설명

Anti-Human HCN2 Polyclonal Antibody (HP198014) is a rabbit polyclonal antibody detecting HCN2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human HCN2 (Gly524-Leu713).

타겟

HCN2, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, BCNG-2, Brain cyclic nucleotide-gated channel 2, BCNG2

정제

Purified by antigen affinity column.

등록번호

Q9UL51

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (HCN2) is a ~96 kDa protein. Hyperpolarization-activated ion channel that is permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Involved in the initiation of neuropathic pain in sensory neurons.

1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147

2. Lolicato, M. et al. (2011) The Journal of biological chemistry 286, 44811-20. PMID: 22006928

3. Vaccari, T. et al. (1999) Biochimica et biophysica acta 1446, 419-25. PMID: 10524219

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human HCN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human HCN2 Polyclonal Antibody (HP198014)

개요

이미지

참고 문헌

데이터시트

SDS