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Anti-Human HDAC7 Polyclonal Antibody (HV082014)

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개요
카탈로그 번호HV082014
설명
Anti-Human HDAC7 Polyclonal Antibody (HV082014) is a rabbit polyclonal antibody detecting HDAC7. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human HDAC7 (Ser482-Ser903).
타겟 EC:3.5.1.-, EC:3.5.1.98, HD7, HD7a, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, Protein deacetylase HDAC7
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 Q8WUI4
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
배경

Histone deacetylase 7 (HDAC7) is a ~102 kDa protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

1. Bryant, H. et al. (2002) Journal of virology 76, 10290-8. PMID: 12239305
2. Li, B. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 4571-6. PMID: 17360565
3. Lee, DY. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 2072-2077. PMID: 28167758
4. Zhang, XL. et al. (2023) Nature communications 14, 3815. PMID: 37369679
참고사항 For research use only
이미지
참고 문헌
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