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Anti-Human HERPUD1 Polyclonal Antibody (HC651014)

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개요
카탈로그 번호HC651014
설명
Anti-Human HERPUD1 Polyclonal Antibody (HC651014) is a rabbit polyclonal antibody detecting HERPUD1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human HERPUD1 (Glu8-Asn87).
타겟 HERPUD1, HERP, Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, MIF1, KIAA0025, Methyl methanesulfonate (MMF)-inducible fragment protein 1
정제 Purified by antigen affinity column.
등록번호 Q15011
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1) is a ~43 kDa protein. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway.

1. Schulze, A. et al. (2005) Journal of molecular biology 354, 1021-7. PMID: 16289116
2. Schulz, J. et al. (2017) Journal of cell science 130, 3322-3335. PMID: 28827405
3. Kim, TY. et al. (2008) Biochemical and biophysical research communications 369, 741-6. PMID: 18307982
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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