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| 카탈로그 번호 | HY418014 | ||||||
|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human HSP90AB1 Polyclonal Antibody (HY418014) is a rabbit polyclonal antibody detecting HSP90AB1. Suitable for Mouse, Human, and Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||
| 응용 분야 | ELISA, IHC, WB | ||||||
| 숙주 종 | Rabbit | ||||||
| 클론성 | Polyclonal | ||||||
| 이소타입 | IgG | ||||||
| 면역원 | E. coli - derived recombinant Human HSP90AB1 (Met1-Asp724). | ||||||
| 타겟 | HSP 84, HSP 90, HSP84, HSP90AB1, HSP90B, HSPC2, HSPC3, HSPCB, Heat shock 84 kDa, Heat shock protein HSP 90-beta, Heat shock protein family C member 3 | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 정제 | Purified by antigen affinity column. | ||||||
| 등록번호 | P08238 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 배경 | Heat shock protein HSP 90-beta (HSP90AB1) is a ~83 kDa protein. Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. 1. Chadli, A. et al. (2006) Molecular and cellular biology 26, 1722-30. PMID: 16478993 2. Retzlaff, M. et al. (2009) EMBO reports 10, 1147-53. PMID: 19696785 3. Pearl, LH. (2016) Biopolymers 105, 594-607. PMID: 26991466 4. Verma, S. et al. (2016) Biochimie 127, 227-40. PMID: 27295069 5. Khurana, N. et al. (2015) Frontiers in oncology 5, 100. PMID: 25973397 6. Shang, Y. et al. (2014) Biochemical and biophysical research communications 446, 387-92. PMID: 24613385 7. Didelot, C. et al. (2008) Cell death and differentiation 15, 859-66. PMID: 18239673 8. Cheng, MB. et al. (2010) Cellular signalling 22, 1206-13. PMID: 20353823 9. Zhang, M. et al. (2020) Cell 181, 637-652.e15. PMID: 32272059 | ||||||
| 참고사항 | For research use only |
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