

| 카탈로그 번호 | HW325014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human HTR7 Polyclonal Antibody (HW325014) is a rabbit polyclonal antibody detecting HTR7 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human HTR7 (Met258-Ala325). | ||||||||
| 타겟 | 5-hydroxytryptamine receptor 7, 5-HT-X, HTR7, 5-HT7, Serotonin receptor 7, 5-HT-7 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P34969 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | 5-hydroxytryptamine receptor 7 (HTR7) is a ~53 kDa protein. G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. 1. Huang, S. et al. (2022) Molecular cell 82, 2681-2695.e6. PMID: 35714614 2. Bard, JA. et al. (1993) The Journal of biological chemistry 268, 23422-6. PMID: 8226867 | ||||||||
| 참고사항 | For research use only. |
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