

| 카탈로그 번호 | HX046014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human ID3 Polyclonal Antibody (HX046014) is a rabbit polyclonal antibody detecting ID3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ID3 (Lys2-Glu86). | ||||||||
| 타겟 | ID3, 1R21, BHLHB25, bHLHb25, Class B basic helix-loop-helix protein 25, Inhibitor of differentiation 3, DNA-binding protein inhibitor ID-3, Inhibitor of DNA binding 3, HEIR1, Helix-loop-helix protein HEIR-1, ID-like protein inhibitor HLH 1R21 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q02535 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | DNA-binding protein inhibitor ID-3 (ID3) is a ~12 kDa protein. Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer. | ||||||||
| 참고사항 | For research use only. |
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