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| 카탈로그 번호 | HT247014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human IDH3B Polyclonal Antibody (HT247014) is a rabbit polyclonal antibody detecting IDH3B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human IDH3B (Ser48-Ser385). | ||||||||
| 타겟 | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta, NAD(+)-specific ICDH subunit beta, IDH3B | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O43837 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) is a ~42 kDa protein. Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-IDH3B polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse heart lysate
Lane 3: Rat heart lysate
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