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| 카탈로그 번호 | HY160014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human IFIT2 Polyclonal Antibody (HY160014) is a rabbit polyclonal antibody detecting IFIT2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human IFIT2 (Met1-Glu472). | ||||||||
| 타겟 | P54, Interferon-induced 54 kDa protein, Interferon-induced protein with tetratricopeptide repeats 2, CIG-42, G10P2, IFI54, IFIT-2, IFI-54K, ISG-54 K, IFIT2, ISG54 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P09913 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) is a ~54 kDa protein. IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. | ||||||||
| 참고사항 | For research use only. |
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