Anti-Human IFITM1 Polyclonal Antibody (HC024014)

Name: Anti-Human IFITM1 Polyclonal Antibody
Brand: abinScience
SKU: HC024014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HC024014

설명

Anti-Human IFITM1 Polyclonal Antibody (HC024014) is a rabbit polyclonal antibody detecting Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD225; IFITM1; CD225; IFI17 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human IFITM1 (His2-His36&Ala58-Asn86&Ser108-Tyr125).

타겟

Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD225; IFITM1; CD225; IFI17

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P13164

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Interferon-induced transmembrane protein 1 (IFITM1) is a ~13 kDa protein. IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV and SARS-CoV-2 S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Inhibits SARS-CoV-2 S protein-mediated syncytia formation.

1. Narayana, SK. et al. (2015) The Journal of biological chemistry 290, 25946-59. PMID: 26354436

2. Shi, G. et al. (2021) The EMBO journal 40, e106501. PMID: 33270927

3. Buchrieser, J. et al. (2020) The EMBO journal 39, e106267. PMID: 33051876

참고사항

For research use only

이미지

Western blot

Lane 1: Jurkat cell lysate
Lane 2: HepG2 cell lysate
Lane 3: K562 cell lysate
Lane 4: HL-60 cell lysate
Lane 5: Hela cell lysate
Lane 6: 293T cell lysate
Lane 7: NIH3T3 cell lysate
Lane 8: MCF-7 cell lysate
Lane 9: Mouse spleen lysate
Lane 10: Mouse testis lysate
Lane11: Mouse brain lysate
Lane12: Rat spleen lysate
Lane13: Rat testis lysate
Lane14: Rat brain lysate

참고 문헌

데이터시트

Anti-Human IFITM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human IFITM1 Polyclonal Antibody (HC024014)

개요

이미지

참고 문헌

데이터시트

SDS