

| 카탈로그 번호 | HP142014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human IFT20 Polyclonal Antibody (HP142014) is a rabbit polyclonal antibody detecting IFT20 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Danio rerio, and Xenopus laevis.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human IFT20 (Met1-Lys132). | ||||||||
| 타겟 | hIFT20, IFT20, Intraflagellar transport protein 20 homolog | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8IY31 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Intraflagellar transport protein 20 homolog (IFT20) is a ~15 kDa protein. Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility. 1. Pugacheva, EN. et al. (2007) Cell 129, 1351-63. PMID: 17604723 2. Follit, JA. et al. (2006) Molecular biology of the cell 17, 3781-92. PMID: 16775004 3. Schmid, FM. et al. (2018) The Journal of cell biology 217, 151-161. PMID: 29237719 | ||||||||
| 참고사항 | For research use only. |
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