Anti-Human IL-13 Recombinant Antibody (SAA0383), APC (HW632237)

Name: Anti-Human IL-13 Recombinant Antibody (SAA0383), APC
Brand: abinScience
SKU: HW632237
Price: 256 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
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개요

카탈로그 번호	HW632237
종 반응성	Human
응용 분야	ELISA, FCM
숙주 종	Human
클론성	Monoclonal
이소타입	IgG4, lambda
클론 ID	SAA0383
접합	APC
타겟	IL-13, IL13, Interleukin-13, NC30
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
관련 제품	Human IgG4, lambda Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호	P35225
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Interleukin-13 (IL13) is a ~15 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B. 1. Minty, A. et al. (1993) Nature 362, 248-50. PMID: 8096327 2. McKenzie, AN. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 3735-9. PMID: 8097324 3. Defrance, T. et al. (1994) The Journal of experimental medicine 179, 135-43. PMID: 7903680 4. Luttmann, W. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 1678-83. PMID: 8759755 5. Schnyder, B. et al. (1996) Blood 87, 4286-95. PMID: 8639787 6. Miloux, B. et al. (1997) FEBS letters 401, 163-6. PMID: 9013879 7. Kasaian, MT. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 561-9. PMID: 21622864
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.