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| 카탈로그 번호 | HV820013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1625 | ||||
| 타겟 | FIL1Z, IL37, Interleukin-1-related protein, IL-23, IL1F7, IL-37, IL1RP1, FIL1 zeta, IL-1X, Interleukin-23, IL-1F7, IL-1RP1, Interleukin-1 family member 7, Interleukin-37, Interleukin-1 homolog 4, Interleukin-1 zeta, IL-1H, IL-1H4, IL-1 zeta, IL1H4 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9NZH6 | ||||
| RRID | Anti-Human IL37/IL1F7 Antibody (SAA1625) (abinScience Cat# HV820013, RRID:AB_3727386) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Interleukin-37 (IL37/IL1F7) is a ~24 kDa protein. Immune regulatory cytokine that acts as a suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. Signaling can occur via two mechanisms, intracellularly through nuclear translocation with SMAD3 and extracellularly after secretion and binding to its receptor composed of IL18R1 and IL18RAP. Suppresses, or reduces, pro-inflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation. | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human IL37/IL1F7 Antibody (SAA1625)
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