Anti-Human IST1 Polyclonal Antibody (HX152014)

Name: Anti-Human IST1 Polyclonal Antibody
Brand: abinScience
SKU: HX152014
Price: 96 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

20ug
50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HX152014

설명

Anti-Human IST1 Polyclonal Antibody (HX152014) is a rabbit polyclonal antibody detecting IST1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human IST1 (Met1-Glu186).

타겟

Putative MAPK-activating protein PM28, IST1, IST1 homolog, KIAA0174, hIST1

정제

Purified by antigen affinity column.

등록번호

P53990

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

IST1 homolog is a ~39 kDa protein. ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation. Is required for efficient abscission during cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing. Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2.

1. Bajorek, M. et al. (2009) Molecular biology of the cell 20, 1360-73. PMID: 19129479

2. Vietri, M. et al. (2015) Nature 522, 231-5. PMID: 26040712

3. Gu, M. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E2166-E2175. PMID: 28242692

4. Agromayor, M. et al. (2009) Molecular biology of the cell 20, 1374-87. PMID: 19129480

5. Allison, R. et al. (2013) The Journal of cell biology 202, 527-43. PMID: 23897888

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human IST1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human IST1 Polyclonal Antibody (HX152014)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기