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Anti-Human JADE1 Polyclonal Antibody (HA939014)

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개요
카탈로그 번호HA939014
설명
Anti-Human JADE1 Polyclonal Antibody (HA939014) is a rabbit polyclonal antibody detecting JADE1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Human, Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human JADE1 (Gly217-Ser363).
타겟 KIAA1807, Jade family PHD finger protein 1, JADE1, PHD finger protein 17, Protein Jade-1, PHF17
정제 Purified by antigen affinity column.
등록번호 Q6IE81
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Protein Jade-1 (JADE1) is a ~95 kDa protein. Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.

1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653
2. Saksouk, N. et al. (2009) Molecular cell 33, 257-65. PMID: 19187766
3. Miotto, B. et al. (2010) Molecular cell 37, 57-66. PMID: 20129055
4. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767
5. Panchenko, MV. et al. (2004) The Journal of biological chemistry 279, 56032-41. PMID: 15502158
6. Zhou, MI. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 11035-40. PMID: 16046545
7. Borgal, L. et al. (2012) The Journal of biological chemistry 287, 25370-80. PMID: 22654112
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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