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Anti-Human LETM1 Polyclonal Antibody (HF870014)

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  • 개요

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개요
카탈로그 번호HF870014
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human LETM1 (Leu231-Thr426).
타겟 LETM1, Leucine zipper-EF-hand-containing transmembrane protein 1, Mitochondrial proton/calcium exchanger protein
정제 Purified by antigen affinity column.
등록번호 O95202
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Mitochondrial proton/calcium exchanger protein (LETM1) is a ~83 kDa protein. Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Also functions as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.

1. Tamai, S. et al. (2008) Journal of cell science 121, 2588-600. PMID: 18628306
2. Jiang, D. et al. (2009) Science (New York, N.Y.) 326, 144-7. PMID: 19797662
3. Tsai, MF. et al. (2014) The Journal of general physiology 143, 67-73. PMID: 24344246
4. De Marchi, U. et al. (2014) The Journal of biological chemistry 289, 20377-85. PMID: 24898248
5. Huang, E. et al. (2017) Nature communications 8, 1399. PMID: 29123128
6. Nakamura, S. et al. (2020) Communications biology 3, 99. PMID: 32139798
7. Kaiyrzhanov, R. et al. (2022) American journal of human genetics 109, 1692-1712. PMID: 36055214
8. Austin, S. et al. (2022) EMBO reports 23, e54978. PMID: 36321428
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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