Anti-Human lgM μ-Chain Specific Recombinant Antibody (HB57), APC (HV496137)

Name: Anti-Human lgM μ-Chain Specific Recombinant Antibody (HB57), APC
Brand: abinScience
SKU: HV496137
Price: 290 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호	HV496137
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1
클론 ID	HB57
접합	APC
타겟	IGHM, Ig mu chain C region, Ig mu chain C region BOT, Ig mu chain C region GAL, Ig mu chain C region OU, Immunoglobulin heavy constant mu
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
관련 제품	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호	P01871
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Immunoglobulin heavy constant mu (lgM) is a ~51 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.