中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HV606013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1616 | ||||
| 타겟 | PRSC1, Legumain, Asparaginyl endopeptidase, LGMN, Protease, cysteine 1 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q99538 | ||||
| RRID | Anti-Human LGMN/Legumain Antibody (SAA1616) (abinScience Cat# HV606013, RRID:AB_3727377) |
||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Legumain (LGMN) is a ~49 kDa protein. Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules. 1. Dall, E. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 10940-5. PMID: 23776206 2. Manoury, B. et al. (1998) Nature 396, 695-9. PMID: 9872320 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human LGMN/Legumain Antibody (SAA1616)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
