Anti-Human LRPPRC Polyclonal Antibody (HC198014)

Name: Anti-Human LRPPRC Polyclonal Antibody
Brand: abinScience
SKU: HC198014
Price: 168 USD
Availability: InStock

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50ug
100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC198014

설명

Anti-Human LRPPRC Polyclonal Antibody (HC198014) is a rabbit polyclonal antibody detecting LRPPRC. Suitable for Human.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human LRPPRC (Thr385-Asp725).

타겟

130 kDa leucine-rich protein, GP130, LRP 130, LRP130, LRPPRC, Leucine-rich PPR motif-containing protein, mitochondrial

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P42704

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) is a ~157 kDa protein. May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. Positively modulates nuclear export of mRNAs containing the EIF4E sensitivity element (4ESE) by binding simultaneously to both EIF4E and the 4ESE and acting as a platform for assembly for the RNA export complex. Also binds to exportin XPO1/CRM1 to engage the nuclear pore and traffic the bound mRNAs to the cytoplasm. May bind mature mRNA in the nucleus outer membrane.

1. Topisirovic, I. et al. (2009) The EMBO journal 28, 1087-98. PMID: 19262567

2. Volpon, L. et al. (2017) RNA (New York, N.Y.) 23, 927-937. PMID: 28325843

3. Zou, J. et al. (2013) The Biochemical journal 454, 447-57. PMID: 23822101

참고사항

For research use only

이미지

Western blot

Western blot analysis was performed using anti-LRPPRC polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: SH-SY5Y cell lysate

참고 문헌

데이터시트

Anti-Human LRPPRC Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human LRPPRC Polyclonal Antibody (HC198014)

개요

이미지

참고 문헌

데이터시트

SDS