Anti-Human LUZP1 Polyclonal Antibody (HC252014)

Name: Anti-Human LUZP1 Polyclonal Antibody
Brand: abinScience
SKU: HC252014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HC252014

설명

Anti-Human LUZP1 Polyclonal Antibody (HC252014) is a rabbit polyclonal antibody detecting LUZP1. Suitable for Human and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human LUZP1 (Met157-Gln350).

타겟

Filamin mechanobinding actin cross-linking protein, Fimbacin, LUZP1, Leucine zipper protein 1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q86V48

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Leucine zipper protein 1 (LUZP1) is a ~120 kDa protein. F-actin cross-linking protein. Stabilizes actin and acts as a negative regulator of primary cilium formation. Positively regulates the phosphorylation of both myosin II and protein phosphatase 1 regulatory subunit PPP1R12A/MYPT1 and promotes the assembly of myosin II stacks within actin stress fibers. Inhibits the phosphorylation of myosin light chain MYL9 by DAPK3 and suppresses the constriction velocity of the contractile ring during cytokinesis. Binds to microtubules and promotes epithelial cell apical constriction by up-regulating levels of diphosphorylated myosin light chain (MLC) through microtubule-dependent inhibition of MLC dephosphorylation by myosin phosphatase.

1. Wang, J. et al. (2019) Biochemistry 58, 4737-4743. PMID: 30990684

2. Gonçalves, J. et al. (2020) The Journal of cell biology 219. PMID: 32496561

3. Wang, L. et al. (2024) Cellular and molecular life sciences : CMLS 81, 248. PMID: 38832964

4. Hyodo, T. et al. (2024) The FEBS journal 291, 927-944. PMID: 38009294

참고사항

For research use only

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참고 문헌

데이터시트

Anti-Human LUZP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human LUZP1 Polyclonal Antibody (HC252014)

개요

이미지

참고 문헌

데이터시트

SDS

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