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| 카탈로그 번호 | HV236014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human LYVE1 Polyclonal Antibody (HV236014) is a rabbit polyclonal antibody detecting LYVE1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human LYVE1 (Arg26-Ser131). | ||||||||
| 타겟 | Cell surface retention sequence-binding protein 1, XLKD1, LYVE-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1, CRSBP-1, LYVE1, CRSBP1, HAR, Lymphatic vessel endothelial hyaluronic acid receptor 1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9Y5Y7 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE1) is a ~35 kDa protein. Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium. 1. Banerji, S. et al. (1999) The Journal of cell biology 144, 789-801. PMID: 10037799 2. Lawrance, W. et al. (2016) The Journal of biological chemistry 291, 8014-30. PMID: 26823460 | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-LYVE1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat brain lysate
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