Anti-Human Tau Recombinant Antibody (IPN-002), PE (HY086127)

Name: Anti-Human Tau Recombinant Antibody (IPN-002), PE
Brand: abinScience
SKU: HY086127
Price: 290 USD
Availability: InStock

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개요
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개요

카탈로그 번호	HY086127
종 반응성	Human
응용 분야	ELISA, FCM
숙주 종	Human
클론성	Monoclonal
이소타입	IgG4, kappa
클론 ID	IPN-002
접합	PE
테스트된 응용 분야	FCM
타겟	MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU
내독소 수준	Please contact with the lab for this information.
순도	>90% as determined by SDS-PAGE.
관련 제품	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), PE
등록번호	P10636
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Microtubule-associated protein tau (MAPT) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

이미지

Flow CytoMetry

Flow-cytometry using PE anti-human MAPT antibody. HDLM-2 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human MAPT monoclonal antibody (Catalog: HY086127, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

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