Anti-Human Tau Recombinant Antibody (MC1) (HY086203)

Name: Anti-Human Tau Recombinant Antibody (MC1)
Brand: abinScience
SKU: HY086203
Price: 126 USD
Availability: InStock

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20ug
50ug
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1mg

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY086203

종 반응성

Human

응용 분야

ELISA, FCM

숙주 종

Mouse

클론성

Monoclonal

이소타입

IgG2a, kappa

클론 ID

MC1

테스트된 응용 분야

FCM

타겟

MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU

내독소 수준

< 10 EU/mg

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P10636

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Microtubule-associated protein tau (MAPT) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311

2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270

참고사항

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

이미지

Flow CytoMetry

Flow-cytometry using FITC anti-human MAPT antibody. HDLM-2 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human MAPT monoclonal antibody (Catalog: HY086203, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

참고 문헌

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