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| 카탈로그 번호 | HY086253 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human MAPT/Tau/PHF-tau Nanobody (SAA2138) [SAA2138] (HY086253) is a alpaca monoclonal antibody detecting PHF-tau in ELISA. Suitable for Human.
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| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, FCM, IHC | ||||
| 숙주 종 | Alpaca | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | VHH-8His-Cys-tag | ||||
| 클론 ID | SAA2138 | ||||
| 타겟 | MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU | ||||
| 내독소 수준 | < 10 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Purified by Nickel column | ||||
| 등록번호 | P10636 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Microtubule-associated protein tau (MAPT) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human MAPT/Tau/PHF-tau Nanobody (SAA2138).
Detects recombinatn tau protein (Catalog No: HY086012) in indirect ELISA.
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
