

| 카탈로그 번호 | HA382014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human MARK4 Polyclonal Antibody (HA382014) is a rabbit polyclonal antibody detecting MARK4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MARK4 (Gly57-Lys370). | ||||||||
| 타겟 | MAP/microtubule affinity-regulating kinase 4, 2.7.11.1, MAP/microtubule affinity-regulating kinase-like 1, MARK4, KIAA1860, MARKL1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q96L34 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | MAP/microtubule affinity-regulating kinase 4 (MARK4) is a ~82 kDa protein. Serine/threonine-protein kinase. Phosphorylates the microtubule-associated protein MAPT/TAU. Also phosphorylates the microtubule-associated proteins MAP2 and MAP4. Involved in regulation of the microtubule network, causing reorganization of microtubules into bundles. Required for the initiation of axoneme extension during cilium assembly. 1. Trinczek, B. et al. (2004) The Journal of biological chemistry 279, 5915-23. PMID: 14594945 2. Schneider, A. et al. (2004) Journal of neurochemistry 88, 1114-26. PMID: 15009667 3. Li, L. et al. (2013) The Journal of biological chemistry 288, 703-8. PMID: 23184942 4. Gu, GJ. et al. (2013) Neuromolecular medicine 15, 458-69. PMID: 23666762 5. Rovina, D. et al. (2014) European journal of cell biology 93, 355-65. PMID: 25123532 6. Kuhns, S. et al. (2013) The Journal of cell biology 200, 505-22. PMID: 23400999 7. Li, X. et al. (2017) Nature communications 8, 15986. PMID: 28656979 | ||||||||
| 참고사항 | For research use only. |
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