Anti-Human MCRS1 Polyclonal Antibody (HA075014)

Name: Anti-Human MCRS1 Polyclonal Antibody
Brand: abinScience
SKU: HA075014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HA075014

설명

Anti-Human MCRS1 Polyclonal Antibody (HA075014) is a rabbit polyclonal antibody detecting MCRS1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human MCRS1 (Gln344-Gln462).

타겟

MCRS1, INO80 complex subunit J, Microspherule protein 1, MCRS2, Cell cycle-regulated factor p78, INO80Q, MSP58, 58 kDa microspherule protein

정제

Purified by antigen affinity column.

등록번호

Q96EZ8

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Microspherule protein 1 (MCRS1) is a ~51 kDa protein. Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex, may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA.

1. Lin, DY. et al. (2002) The Journal of biological chemistry 277, 25446-56. PMID: 11948183

2. Cai, Y. et al. (2010) The Journal of biological chemistry 285, 4268-72. PMID: 20018852

3. Song, H. et al. (2004) Biochemical and biophysical research communications 316, 1116-23. PMID: 15044100

4. Davidovic, L. et al. (2006) Human molecular genetics 15, 1525-38. PMID: 16571602

5. Fawal, MA. et al. (2015) Developmental cell 33, 67-81. PMID: 25816988

6. Meunier, S. et al. (2011) Nature cell biology 13, 1406-14. PMID: 22081094

7. Meunier, S. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 1779-86. PMID: 27192185

8. Yang, H. et al. (2019) Molecular biology of the cell 30, 1060-1068. PMID: 30785839

9. Laguillo-Diego, A. et al. (2023) Molecular biology of the cell 34, ar1. PMID: 36350698

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human MCRS1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human MCRS1 Polyclonal Antibody (HA075014)

개요

이미지

참고 문헌

데이터시트

SDS

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