Anti-Human METTL5 Polyclonal Antibody (HA273014)

Name: Anti-Human METTL5 Polyclonal Antibody
Brand: abinScience
SKU: HA273014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA273014

설명

Anti-Human METTL5 Polyclonal Antibody (HA273014) is a rabbit polyclonal antibody detecting METTL5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human METTL5 (Met1-Phe209).

타겟

Methyltransferase-like protein 5, METTL5, rRNA N6-adenosine-methyltransferase METTL5

정제

Purified by antigen affinity column.

등록번호

Q9NRN9

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

rRNA N(6)-adenosine-methyltransferase METTL5 is a ~23 kDa protein. Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA. N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation.

1. van Tran, N. et al. (2019) Nucleic acids research 47, 7719-7733. PMID: 31328227

2. Ignatova, VV. et al. (2020) Genes & development 34, 715-729. PMID: 32217665

3. Rong, B. et al. (2020) Cell reports 33, 108544. PMID: 33357433

4. Yu, D. et al. (2021) The Journal of biological chemistry 296, 100270. PMID: 33428944

5. Sepich-Poore, C. et al. (2022) The Journal of biological chemistry 298, 101590. PMID: 35033535

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-METTL5 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate

참고 문헌

데이터시트

Anti-Human METTL5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human METTL5 Polyclonal Antibody (HA273014)

개요

이미지

참고 문헌

데이터시트

SDS