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| 카탈로그 번호 | HD596014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human MOGAT2 Polyclonal Antibody (HD596014) is a rabbit polyclonal antibody detecting MOGAT2. Suitable for Human.
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MOGAT2 (His70-Cys334). | ||||||||
| 타겟 | 2-acylglycerol O-acyltransferase 2, Acyl-CoA:monoacylglycerol acyltransferase 2, DC5, DGAT2L5, Diacylglycerol O-acyltransferase candidate 5, Diacylglycerol acyltransferase 2-like protein 5, EC:2.3.1.20, EC:2.3.1.22, MGAT2, MOGAT2, Monoacylglycerol O-acyltransferase 2, hDC5, hMGAT2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q3SYC2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | 2-acylglycerol O-acyltransferase 2 (MOGAT2) is a ~38 kDa protein. Involved in glycerolipid synthesis and lipid metabolism. Catalyzes the formation of diacylglycerol, the precursor of triacylglycerol, by transferring the acyl chain of a fatty acyl-CoA to a monoacylglycerol. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0 at sn-2. Able to use 1-monoalkylglycerol (1-MAkG, 1-O-alkylglycerol) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG, 1-O-alkyl-3-acylglycerol or 1-O-alkyl-2-acylglycerol) and subsequently, with lower efficiency, may add another acyl chain producing monoalkyl-diacylglycerol (MADAG, 1-O-alkyl-2,3-diacylglycerol). 1. Yen, CL. et al. (2003) The Journal of biological chemistry 278, 18532-7. PMID: 12621063 2. Cheng, D. et al. (2008) The Journal of biological chemistry 283, 29802-11. PMID: 18768481 3. Brandt, C. et al. (2016) Biochemical and biophysical research communications 475, 264-70. PMID: 27184406 4. Ma, Z. et al. (2017) Journal of lipid research 58, 1091-1099. PMID: 28420705 | ||||||||
| 참고사항 | For research use only |
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