中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HY280033 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||
| 응용 분야 | ELISA, FACS, Functional assay, Research in vivo | ||||
| 숙주 종 | Armenian hamster | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG | ||||
| 클론 ID | 2H5 | ||||
| 타겟 | C-C motif chemokine 2, CCL2, HC11, MCAF, MCP-1, MCP1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2 | ||||
| 내독소 수준 | <1 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 관련 제품 | pH 7.4 Dilution Buffer | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P13500, P10148, P14844 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | C-C motif chemokine 2 (CCL2/MCP-1) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. 1. Hemmerich, S. et al. (1999) Biochemistry 38, 13013-25. PMID: 10529171 2. Jarnagin, K. et al. (1999) Biochemistry 38, 16167-77. PMID: 10587439 3. Paavola, CD. et al. (1998) The Journal of biological chemistry 273, 33157-65. PMID: 9837883 4. Zhang, YJ. et al. (1994) The Journal of biological chemistry 269, 15918-24. PMID: 8195247 5. Weber, M. et al. (1996) The Journal of experimental medicine 183, 681-5. PMID: 8627182 6. Chakravarty, L. et al. (1998) The Journal of biological chemistry 273, 29641-7. PMID: 9792674 7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690 | ||||
| 참고사항 | For research use only |
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
