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| 카탈로그 번호 | HC456014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human MRPL58 Polyclonal Antibody (HC456014) is a rabbit polyclonal antibody detecting MRPL58 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MRPL58 (Asp71-Asp206). | ||||||||
| 타겟 | DS1, MRPL58, Immature colon carcinoma transcript 1 protein, Digestion substraction 1, Mitochondrial large ribosomal subunit protein mL62, DS-1, ICT1, MRP-L58, Peptidyl-tRNA hydrolase ICT1, mitochondrial, 39S ribosomal protein L58, mitochondrial | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q14197 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Large ribosomal subunit protein mL62 (MRPL58) is a ~23 kDa protein. Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. Involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. 1. Richter, R. et al. (2010) The EMBO journal 29, 1116-25. PMID: 20186120 2. Kummer, E. et al. (2021) Molecular cell 81, 2566-2582.e6. PMID: 33878294 | ||||||||
| 참고사항 | For research use only. |
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