

| 카탈로그 번호 | HA093014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human MTA3 Polyclonal Antibody (HA093014) is a rabbit polyclonal antibody detecting MTA3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MTA3 (Met1-Lys147). | ||||||||
| 타겟 | Metastasis-associated protein MTA3, MTA3, KIAA1266 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9BTC8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Metastasis-associated protein MTA3 is a ~67 kDa protein. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6. 1. Fujita, N. et al. (2003) Cell 113, 207-19. PMID: 12705869 2. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440 3. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666 4. Fujita, N. et al. (2004) Cell 119, 75-86. PMID: 15454082 | ||||||||
| 참고사항 | For research use only. |
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