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| 카탈로그 번호 | HC278014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human MTAP Polyclonal Antibody (HC278014) is a rabbit polyclonal antibody detecting MTAP in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Macaca mulatta.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MTAP (Met1-His283). | ||||||||
| 타겟 | MTAP, S-methyl-5'-thioadenosine phosphorylase, MSAP, MTA phosphorylase, 5'-methylthioadenosine phosphorylase, MTAPase | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q13126 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | S-methyl-5'-thioadenosine phosphorylase (MTAP) is a ~31 kDa protein. Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-MTAP polyclonal antibody at 1μg/ml on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: HT-29 cell lysate
Lane 3: Raji cell lysate
Lane 4: Hela cell lysate
Lane 5: HCT116 cell lysate
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