Anti-Human MTM1 Recombinant Antibody (SAA1671) (HC500013)

Name: Anti-Human MTM1 Recombinant Antibody (SAA1671)
Brand: abinScience
SKU: HC500013
Price: 196 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC500013

종 반응성

Human

응용 분야

ELISA

숙주 종

Mouse

클론성

Monoclonal

이소타입

IgG2a, kappa

클론 ID

SAA1671

타겟

Myotubularin, Phosphatidylinositol-3, 5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase, MTM1, CG2

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

Q13496

RRID

Anti-Human MTM1 Antibody (SAA1671) (abinScience Cat# HC500013, RRID:AB_3727432)

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

배경

Myotubularin (MTM1) is a ~69 kDa protein. Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture.

1. Taylor, GS. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8910-5. PMID: 10900271

2. Blondeau, F. et al. (2000) Human molecular genetics 9, 2223-9. PMID: 11001925

3. Schaletzky, J. et al. (2003) Current biology : CB 13, 504-9. PMID: 12646134

4. Tsujita, K. et al. (2004) The Journal of biological chemistry 279, 13817-24. PMID: 14722070

5. Cui, X. et al. (1998) Nature genetics 18, 331-7. PMID: 9537414

6. Hnia, K. et al. (2011) The Journal of clinical investigation 121, 70-85. PMID: 21135508

7. Gupta, VA. et al. (2013) PLoS genetics 9, e1003583. PMID: 23818870

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Human MTM1 Antibody (SAA1671)

참고 문헌

데이터시트

Anti-Human MTM1 Recombinant Antibody (SAA1671).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human MTM1 Recombinant Antibody (SAA1671) (HC500013)

개요

이미지

참고 문헌

데이터시트

SDS

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