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| 카탈로그 번호 | HC499014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human MYO9B (Pro1691-Ala1916). | ||||||||
| 타겟 | MYO9B, Unconventional myosin-IXb, MYR5, Unconventional myosin-9b | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q13459 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Unconventional myosin-IXb (MYO9B) is a ~243 kDa protein. Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activator for RHOA. Plays a role in the regulation of cell migration via its role as RHOA GTPase activator. 1. Post, PL. et al. (1998) Journal of cell science 111 ( Pt 7), 941-50. PMID: 9490638 2. Kong, R. et al. (2015) The Journal of clinical investigation 125, 4407-20. PMID: 26529257 | ||||||||
| 참고사항 | For research use only. |
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